NFL players from Kentucky, Louisville, Eastern Kentucky and Western Kentucky
| Kentucky | ||
| PLAYER | TEAM | POSITION |
| Randall Cobb | Green Bay Packers | Wide Receiver |
| DeQuin Evans | Cincinnati Bengals | Defensive End |
| Winston Guy | Jacksonville Jaguars | Safety |
| Steve Johnson | Buffalo Bills | Wide Receiver |
| Tim Masthay | Green Bay Packers | Punter |
| Corey Peters | Atlanta Falcons | Defensive Tackle |
| Alfonso Smith | Arizona Cardinals | Running Back |
| Jacob Tamme | Denver Broncos | Tight End |
| Danny Trevathan | Denver Broncos | Linebacker |
| Larry Warford | Detroit Lions | Guard |
| Garry Williams | Carolina Panthers | Offensive Tackle |
| Wesley Woodyard | Denver Broncos | Linebacker |
| Louisville | ||
| PLAYER | TEAM | POSITION |
| David Akers | Detroit Lions | Place kicker |
| Gary Barnidge | Cleveland Browns | Tight End |
| Michael Bush | Chicago Bears | Running Back |
| Harry Douglas | Atlanta Falcons | Wide Receiver |
| Elvis Dumervil | Baltimore Ravens | Linebacker |
| William Gay | Pittsburgh Steelers | Cornerback |
| Breno Giacomini | Seattle Seahawks | Offensive Tackle |
| Johnny Patrick | San Diego Chargers | Cornerback |
| Bilal Powell | New York Jets | Running Back |
| Greg Scruggs | Seattle Seahawks | Defensive End |
| Byron Stingily | Tennessee Titans | Offensive Tackle |
| Eric Wood | Buffalo Bills | Center |
| Western Kentucky | ||
| PLAYER | TEAM | POSITION |
| Jack Doyle | Indianapolis Colts | Tight End |
| Bobby Rainey | Cleveland Browns | Running Back |
| Quanterus Smith | Denver Broncos | Defensive End |
| Eastern Kentucky | ||
| PLAYER | TEAM | POSITION |
| Yeremiah Bell | Arizona Cardinals | Safety |