| Thursday, November 3, 2022 |
| Central | 1 | vs. Marion County | 0 | Class 4A 2022 UK HealthCare Sports Medicine State Football Finals
Forfeit, Depleted Number of Players | ⇄ |
| Owensboro | 54 | vs. Christian County | 16 | Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| St. Xavier | 53 | vs. Southern | 0 | Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Friday, November 4, 2022 |
| Bardstown | 1 | vs. Western Hills | 0 | Class 3A 2022 UK HealthCare Sports Medicine State Football Finals
Forfeit, depleted number of participants | ⇄ |
| Fairview | – | at Bishop Brossart | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Fort Knox | – | at Crittenden County | – | 6:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Berea | – | at Dayton | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Newport Central Catholic | – | vs.Eminence
(at Dixie Heights HS) | – | 7:00 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Ludlow | – | at Frankfort | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Sayre | – | at Harlan | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Pineville | – | at Hazard | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Bracken County | – | at Paintsville | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Betsy Layne | – | at Paris | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Lynn Camp | – | at Pikeville | – | 7:00 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Nicholas County | – | at Raceland | – | 7:30 PM Class 1A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Holy Cross (Louisville) | – | at Russellville | – | 7:00 PM Class 1A 2022 UK HealthCare Sports Medic
ine State Football Finals | ⇄ |
| Trimble County | – | at Beechwood | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| West Carter | – | at Breathitt County | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Murray | – | at Butler County | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| McLean County | – | at Caldwell County | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Holy Cross (Covington) | – | at Carroll County | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Monroe County | – | at Danville | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Somerset | – | at Green County | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Edmonson County | – | at Lexington Christian | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Owen County | – | at Lloyd Memorial | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Leslie County | – | at Martin County | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Todd County Central | – | at Mayfield | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Washington County | – | at Metcalfe County | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Prestonsburg | – | at Middlesboro | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Morgan County | – | at Shelby Valley | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Owensboro Catholic | – | vs.Fort Campbell
(at Steele Stadium, KWC) | – | 7:00 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Newport | – | at Walton-Verona | – | 7:30 PM Class 2A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Magoffin County | – | at Ashland Blazer | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Russell | – | at Belfry | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Powell County | – | at Bell County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Webster County | – | at Casey County | – | 8:00 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| LaRue County | – | at Christian Academy-Louisville | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Mercer County | – | at Elizabethtown | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Lewis County | – | at Estill County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Garrard County | – | at Fleming County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Pike County Central | – | at Greenup County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Trigg County | – | at Hart County | – | 7:00 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Nelson County | – | at Henry County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| East Carter | – | at Lawrence County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Rockcastle County | – | at Mason County | – | 7:30 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Taylor County | – | at Paducah Tilghman | – | 7:00 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Glasgow | – | at Union County | – | 7:00 PM Class 3A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Anderson County | – | at Boyd Coun
ty | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Rowan County | – | at Boyle County | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Harlan County | – | at Corbin | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| John Hardin | – | at Franklin County | – | 8:00 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Hopkinsville | – | at Franklin-Simpson | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Bourbon County | – | at Holmes | – | 7:00 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Lincoln County | – | at Johnson Central | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Knox Central | – | at Letcher County Central | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Scott | – | at Lexington Catholic | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Allen County-Scottsville | – | at Logan County | – | 7:00 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Warren Central | – | at Madisonville-North Hopkins | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Shelby County | – | at Spencer County | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| North Oldham | – | at Valley | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Hopkins County Central | – | at Warren East | – | 7:00 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Clay County | – | at Wayne County | – | 7:30 PM Class 4A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Doss | – | at Atherton | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Ohio County | – | at Bowling Green | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Seneca | – | at Bullitt Central | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| North Laurel | – | at Collins | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Great Crossing | – | at Covington Catholic | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| North Bullitt | – | at Fairdale | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Conner | – | at Frederick Douglass | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| South Warren | – | at Graves County | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Grayson County | – | at Greenwood | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Montgomery County | – | at Highlands | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| West Jessamine | – | at Pulaski County | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Cooper | – | at Scott County | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Western | – | at South Oldham | – | 7:00 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Madison Southern | – | at Southwestern | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Whitley County | – | at Woodford County | – | 7:30 PM Class 5A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Dixie Heights | – | at Ballard | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Lafayette | – | at Bryan Station | – | 6:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Butler | – | a
t Bullitt East | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Apollo | – | at Central Hardin | – | 8:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| North Hardin | – | at Daviess County | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Fern Creek | – | at DuPont Manual | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Barren County | – | at Henderson County | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Henry Clay | – | at Madison Central | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Pleasure Ridge Park | – | at Male | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| McCracken County | – | at Meade County | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Oldham County | – | at Paul Laurence Dunbar | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Eastern | – | at Ryle | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Marshall County | – | at Simon Kenton | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| George Rogers Clark | – | at Tates Creek | – | 7:00 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals | ⇄ |
| Campbell County | – | at Trinity (Louisville) | – | 7:30 PM Class 6A 2022 UK HealthCare Sports Medicine State Football Finals |
